NanoString Blog
CosMx SMI
How CosMx SMI Enables Next-Generation Spatially Resolved Cell Assays with Subcellular Resolution
The ability to simultaneously map morphology, RNA, and protein at the subcellular level is the new frontier in cell biology. While the CosMx® Spatial Molecular Imager (SMI) is renowned for…
CosMx SMI
Why Transcriptomics Matters: Understanding the Value of High-Resolution Spatial Molecular Imaging
As spatial biology reshapes the future of biomedical research, spatial transcriptomics has emerged as one of the most powerful tools for revealing complex tissue biology. Technologies like the CosMx® Spatial…
CosMx SMI
Tips to optimize the CosMx Multiomics sample prep for fragile tissues
Tips to optimize the CosMx Multiomics sample prep for fragile tissues The CosMx multiomics platform enables sequential protein and RNA analysis on the same tissue sample, combining a 64-plex protein…
Miscellaneous
Understanding Bulk Multiomics: A Technical Introduction
Miscellaneous
October 2025 Newsletter
This month brings exciting milestones across our portfolio. Washington University School of Medicine’s Orr Lab has been named a Bruker Spatial Biology Center of Excellence, marking a new chapter in…
CosMx SMI
The CosMx SMI 2.0: Unmatched advances in single-cell spatial transcriptomics
Explore the CosMx SMI 2.0: Higher RNA sensitivity, whole transcriptome imaging, and faster high fidelity, subcellular spatial transcriptomics.
CosMx SMI
Tips to optimize sample prep for highly autofluorescent samples on CosMx® SMI
The CosMx® Spatial Molecular Imager (SMI) instrument performs fluorescent imaging to read out in-situ hybridized fluorescent reporters which uniquely identify RNA transcripts. The presence of tissue autofluorescence background may reduce…
CosMx SMI
Moving Beyond scRNA-seq: The Power of CosMx Whole Transcriptome
Compare CosMx SMI versus scRNA-seq and see how spatial transcriptomics reveals more biology in intact tissue and with subcellular resolution.
Events
Breakthroughs in Spatial Biology: AGBT 2025 Highlights
Discover the future of spatial biology! Read about our AGBT 2025 eBook featuring posters highlighting powerful new breakthroughs EpicIF, CosMx WTX, and InSituDiff, plus on-demand workshop access.
CosMx SMI
Revealing Spatial Biology at Whole-Transcriptome Scale: Introducing the CosMx® Human Whole Transcriptome Panel
Learn how CosMx WTX brings whole-transcriptome coverage to every cell in FFPE tissues, uncovering truly groundbreaking spatial biology.
Neuroscience
Miranda Orr’s Spatial Analyses from Discovery to Validation Reveal Key Processes in Alzheimer’s Disease
Discover Dr. Miranda Orr’s cutting-edge spatial multiomics research in neuroscience, revealing new Alzheimer’s disease processes with advanced proteomic tools.
Spatial Biology
Introducing Enhanced Photobleaching in Cyclic Immunofluorescence for Spatial Biology
FFPE tonsil, captured on the CellScape Platform with EpicIF Technology. Bruker Spatial Biology is pleased to introduce EpicIF™ signal removal technology for the CellScape™ Precise Spatial Proteomics platform. EpicIF technology empowers high-plex…