CosMx® SMI Software Update Files
Software Update Files
This page contains the latest files to update the CosMx® Spatial Molecular Imager on-instrument Software.
Please select the file below that matches the version of the CosMx Control Center Software that you are interested in installing. Always download the Setup and .upg files during updates and ensure that the Control Center Version number for both matches the version number you intend to update to. For OS updates, only the CosMxOSSetup.msi file is required. If you do not see the file you need, please contact spatial.support.bsb@bruker.com for assistance.
CosMx Software Update Files
| Associated Version | File Description | File size | Required? | File |
|---|---|---|---|---|
| v2.2 | CosMx Windows OS Updater November 2025 (for Control Center v2.2) | (TBD) | No | (TBD) |
| v2.1 | CosMx Windows OS Updater July 2025 (for Control Center v2.1) | 889.6MB | No | CosMxOSSetup_19044.6093-2025-07.msi |
| v2.1 | CosMx Control Center SW v2.1 | (TBD) | Yes | (TBD) |
| v2.0 | CosMx Hibernation File (for Control Center v2.0 Software) | 1.22GB | No | HibernatePrepSetup_2.0.0.msi |
| v1.5 | CosMx Hibernation File (for Control Center v1.5 Software) | 1.22GB | No | HibernatePrepSetup_1.5.1.msi |
| v1.4 | CosMx Hibernation File (for Control Center v1.4 Software) | 1.21GB | No | HibernatePrepSetup_1.4.1.msi |
| v1.3 | CosMx Hibernation File (for Control Center v1.3 Software) | 1.26GB | No | HibernatePrepSetup_1.3.0.msi |